1RZJ

HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B

1RZJ の概要

• エントリーDOI: 10.2210/pdb1rzj/pdb
• 関連するPDBエントリー: 1G9M 1RZ7 1RZ8 1RZF 1RZG 1RZI 1RZK
• 分子名称: ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, LIGHT CHAIN, ... (8 entities in total)
• 機能のキーワード: complex (hiv envelope protein-cd4-fab); hiv-1 exterior envelope gp120 from laboratory-adapted isolate; hxbc2; surface t-cell glycoprotein cd4; antigen-binding fragment of human immunoglobulin 17b, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107238.93

構造登録者

Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D. (登録日: 2003-12-24, 公開日: 2004-02-03, 最終更新日: 2021-10-27)

• 主引用文献: Huang, C.C.,Venturi, M.,Majeed, S.,Moore, M.J.,Phogat, S.,Zhang, M.-Y.,Dimitrov, D.S.,Hendrickson, W.A.,Robinson, J.,Sodroski, J.,Wyatt, R.,Choe, H.,Farzan, M.,Kwong, P.D.; Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120; Proc.Natl.Acad.Sci.USA, 101:2706-2711, 2004; PubMed: 14981267; DOI: 10.1073/pnas.0308527100

実験手法

X-RAY DIFFRACTION (2.2 Å)