1RZJ
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G | ENVELOPE GLYCOPROTEIN GP120 | polymer | 321 | 35429.1 | 1 | UniProt (P04578) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
| 2 | C | T-CELL SURFACE GLYCOPROTEIN CD4 | polymer | 185 | 20503.3 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) In PDB | Homo sapiens (human) | |
| 3 | L | ANTIBODY 17B, LIGHT CHAIN | polymer | 214 | 23399.9 | 1 | Homo sapiens (human) | ||
| 4 | H | ANTIBODY 17B, HEAVY CHAIN | polymer | 229 | 24457.4 | 1 | Homo sapiens (human) | ||
| 5 | A, B | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 6 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 7 | G | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 8 | water | water | 18.0 | 586 | Chemie (HOH) |
Sequence modifications
G: 195 - 492 (UniProt: P04578)
C: 1 - 185 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Gly 79 | - | insertion |
| Ala 80 | - | insertion |
| Arg 81 | - | insertion |
| Ser 82 | - | insertion |
| Glu 83 | - | insertion |
| Val 84 | - | insertion |
| Val 85 | - | insertion |
| Leu 86 | - | insertion |
| Val 87 | - | insertion |
| Asn 88 | - | insertion |
| Val 89 | - | insertion |
| Thr 90 | - | insertion |
| Glu 91 | - | insertion |
| Asn 92 | - | insertion |
| Phe 93 | - | insertion |
| Asn 94 | - | insertion |
| Met 95 | - | insertion |
| Trp 96 | - | insertion |
| Lys 97 | - | insertion |
| Asn 98 | - | insertion |
| Asp 99 | - | insertion |
| Met 100 | - | insertion |
| Val 101 | - | insertion |
| Glu 102 | - | insertion |
| Gln 103 | - | insertion |
| Met 104 | - | insertion |
| His 105 | - | insertion |
| Glu 106 | - | insertion |
| Asp 107 | - | insertion |
| Ile 108 | - | insertion |
| Ile 109 | - | insertion |
| Ser 110 | - | insertion |
| Leu 111 | - | insertion |
| Trp 112 | - | insertion |
| Asp 113 | - | insertion |
| Gln 114 | - | insertion |
| Ser 115 | - | insertion |
| Leu 116 | - | insertion |
| Lys 117 | - | insertion |
| Pro 118 | - | insertion |
| Cys 119 | - | insertion |
| Val 120 | - | insertion |
| Lys 121 | - | insertion |
| Leu 122 | - | insertion |
| Thr 123 | - | insertion |
| Pro 124 | - | insertion |
| Leu 125 | - | insertion |
| Cys 126 | - | insertion |
| Val 127 | - | insertion |
| Gly 128 | - | insertion |
| Ala 129 | - | insertion |
| Gly 194 | - | insertion |
| - | Arg 298 | deletion |
| - | Pro 299 | deletion |
| - | Asn 300 | deletion |
| - | Asn 301 | deletion |
| - | Asn 302 | deletion |
| - | Thr 303 | deletion |
| - | Arg 304 | deletion |
| - | Lys 305 | deletion |
| - | Arg 306 | deletion |
| - | Ile 307 | deletion |
| - | Arg 308 | deletion |
| - | Ile 309 | deletion |
| - | Gln 310 | deletion |
| - | Arg 311 | deletion |
| - | Gly 312 | deletion |
| - | Pro 313 | deletion |
| - | Arg 315 | deletion |
| - | Phe 317 | deletion |
| - | Val 318 | deletion |
| - | Thr 319 | deletion |
| - | Ile 320 | deletion |
| - | Gly 321 | deletion |
| - | Lys 322 | deletion |
| - | Ile 323 | deletion |
| - | Asn 325 | deletion |
| - | Met 326 | deletion |
| - | Arg 327 | deletion |
| - | Gln 328 | deletion |
| - | Ala 329 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Asn 184 | Ser 209 | engineered mutation |
| Thr 185 | Ile 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103789.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 734.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2714.6 | |
| All* | Total formula weight | 107238.9 |
