1R9Y

Bacterial cytosine deaminase D314A mutant.

Summary for 1R9Y

Related1K6W 1R9X 1R9Z 1RA0 1RA5 1RAK 1RB7
DescriptorCytosine deaminase, FE (III) ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordscytosine deaminase, amino hydrolase, alpha-beta barrel, hexamer, domain swap, d314a mutant, hydrolase
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight47988.23
Authors
Mahan, S.D.,Ireton, G.C.,Stoddard, B.L.,Black, M.E. (deposition date: 2003-10-31, release date: 2004-10-05, Last modification date: 2011-07-13)
Primary citation
Mahan, S.D.,Ireton, G.C.,Knoeber, C.,Stoddard, B.L.,Black, M.E.
Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy.
Protein Eng.Des.Sel., 17:625-633, 2004
PubMed: 15381761 (PDB entries with the same primary citation)
DOI: 10.1093/protein/gzh074
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.57 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.186400.3%6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution