1R9X

Bacterial cytosine deaminase D314G mutant.

Summary for 1R9X

Related1K6W 1R9Y 1R9Z 1RA0 1RA5 1RAK 1RB7
DescriptorCytosine deaminase, FE (III) ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordscytosine deaminase, hydrolase, alpha-beta barrel, hexamer, domain swap, d314g mutant
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight47974.21
Authors
Mahan, S.D.,Ireton, G.C.,Stoddard, B.L.,Black, M.E. (deposition date: 2003-10-31, release date: 2004-10-05, Last modification date: 2011-07-13)
Primary citation
Mahan, S.D.,Ireton, G.C.,Knoeber, C.,Stoddard, B.L.,Black, M.E.
Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy.
Protein Eng.Des.Sel., 17:625-633, 2004
PubMed: 15381761 (PDB entries with the same primary citation)
DOI: 10.1093/protein/gzh074
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.58 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.184400.6%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution