1QPC

STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS

Summary for 1QPC

Entry DOI	10.2210/pdb1qpc/pdb
Related	1QPD 1QPE 1QPJ
Descriptor	Tyrosine-protein kinase Lck, SULFATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	alpha beta fold, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P06239
Total number of polymer chains	1
Total formula weight	33210.27
Authors	Zhu, X.,Kim, J.L.,Rose, P.E.,Stover, D.R.,Toledo, L.M.,Zhao, H.,Morgenstern, K.A. (deposition date: 1999-05-21, release date: 2000-05-24, Last modification date: 2015-08-19)
Primary citation	Zhu, X.,Kim, J.L.,Newcomb, J.R.,Rose, P.E.,Stover, D.R.,Toledo, L.M.,Zhao, H.,Morgenstern, K.A. Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors. Structure Fold.Des., 7:651-661, 1999 Cited by PubMed: 10404594 DOI: 10.1016/S0969-2126(99)80086-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation