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1QPC

STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATyrosine-protein kinase Lckpolymer27932353.81UniProt (P06239)
Pfam (PF07714)
In PDB
Homo sapiens (human)Leukocyte C-terminal Src kinase, LSK, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase, p56-LCK
2ASULFATE IONnon-polymer96.13Chemie (SO4)
3APHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4A1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5waterwater18.0254Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32353.8
Non-Polymers*Number of molecules5
Total formula weight856.5
All*Total formula weight33210.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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