1OC0
plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin
Summary for 1OC0
Entry DOI | 10.2210/pdb1oc0/pdb |
Related | 1A7C 1B3K 1C5G 1DB2 1DVM 1DVN 1LJ5 9PAI |
Descriptor | PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN (3 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, serine protease inhibitor-complex, serpin, proteinase inhibitor, fibrinolysis, cell migration, plasminogen activation, heparin-binding, cell adhesion, hydrolase/inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P05121 Secreted, extracellular space: P04004 |
Total number of polymer chains | 2 |
Total formula weight | 48606.52 |
Authors | Read, R.J.,Zhou, A.,Huntington, J.A.,Pannu, N.S.,Carrell, R.W. (deposition date: 2003-02-03, release date: 2003-06-19, Last modification date: 2023-12-13) |
Primary citation | Zhou, A.,Huntington, J.A.,Pannu, N.S.,Carrell, R.W.,Read, R.J. How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration Nat.Struct.Biol., 10:541-, 2003 Cited by PubMed: 12808446DOI: 10.1038/NSB943 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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