Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1OC0

plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0002020molecular_functionprotease binding
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005102molecular_functionsignaling receptor binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005886cellular_componentplasma membrane
A0010469biological_processregulation of signaling receptor activity
A0010757biological_processnegative regulation of plasminogen activation
A0010951biological_processnegative regulation of endopeptidase activity
A0014912biological_processnegative regulation of smooth muscle cell migration
A0030194biological_processpositive regulation of blood coagulation
A0030195biological_processnegative regulation of blood coagulation
A0030336biological_processnegative regulation of cell migration
A0031093cellular_componentplatelet alpha granule lumen
A0032757biological_processpositive regulation of interleukin-8 production
A0033629biological_processnegative regulation of cell adhesion mediated by integrin
A0035491biological_processpositive regulation of leukotriene production involved in inflammatory response
A0042730biological_processfibrinolysis
A0045766biological_processpositive regulation of angiogenesis
A0048260biological_processpositive regulation of receptor-mediated endocytosis
A0050729biological_processpositive regulation of inflammatory response
A0050829biological_processdefense response to Gram-negative bacterium
A0051918biological_processnegative regulation of fibrinolysis
A0061044biological_processnegative regulation of vascular wound healing
A0061045biological_processnegative regulation of wound healing
A0062023cellular_componentcollagen-containing extracellular matrix
A0070062cellular_componentextracellular exosome
A0071222biological_processcellular response to lipopolysaccharide
A0090026biological_processpositive regulation of monocyte chemotaxis
A0090399biological_processreplicative senescence
A0097180cellular_componentserine protease inhibitor complex
A0097187biological_processdentinogenesis
A1901331biological_processpositive regulation of odontoblast differentiation
A1902042biological_processnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors
A1904090cellular_componentpeptidase inhibitor complex
A2000098biological_processnegative regulation of smooth muscle cell-matrix adhesion
A2000352biological_processnegative regulation of endothelial cell apoptotic process
B0005044molecular_functionscavenger receptor activity
B0006955biological_processimmune response
B0030247molecular_functionpolysaccharide binding
Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. IIIDRPFLFvV
ChainResidueDetails
AILE352-VAL362

site_idPS00524
Number of Residues21
DetailsSMB_1 Somatomedin B domain (SMB) signature. CqCdelCsyyqs.CCtDYtaeC
ChainResidueDetails
BCYS19-CYS39

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by CK2; in vitro => ECO:0000269|PubMed:9733784
ChainResidueDetails
BTHR50

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine
ChainResidueDetails
AASN209
AASN265

site_idSWS_FT_FI3
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN329

219140

PDB entries from 2024-05-01

PDB statisticsPDBj update infoContact PDBjnumon