1OC0
plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PLASMINOGEN ACTIVATOR INHIBITOR-1 | polymer | 379 | 42782.0 | 1 | UniProt (P05121) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | ENDOTHELIAL PLASMINOGEN ACTIVATOR INHIBITOR, PAI-1, PAI |
| 2 | B (B) | VITRONECTIN | polymer | 51 | 5824.5 | 1 | UniProt (P04004) Pfam (PF01033) | HOMO SAPIENS (HUMAN) | SERUM SPREADING FACTOR, S-PROTEIN, S75 |
| 3 | C, D (A, B) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A: 1 - 379 (UniProt: P05121)
| PDB | External Database | Details |
|---|---|---|
| His 150 | Asn 173 | engineered mutation |
| Thr 154 | Lys 177 | engineered mutation |
| Leu 319 | Gln 342 | engineered mutation |
| Ile 354 | Met 377 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48606.5 | |
| All* | Total formula weight | 48606.5 |
