1NW3

Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

Summary for 1NW3

• Entry DOI: 10.2210/pdb1nw3/pdb
• Descriptor: histone methyltransferase DOT1L, ACETATE ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hdot1, histone lysine methyltransferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q8TEK3
• Total number of polymer chains: 1
• Total formula weight: 48155.76

Authors

Min, J.R.,Feng, Q.,Li, Z.H.,Zhang, Y.,Xu, R.M. (deposition date: 2003-02-05, release date: 2003-03-25, Last modification date: 2024-02-14)

• Primary citation: Min, J.,Feng, Q.,Li, Z.,Zhang, Y.,Xu, R.M.; Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase; Cell(Cambridge,Mass.), 112:711-723, 2003; PubMed: 12628190; DOI: 10.1016/S0092-8674(03)00114-4

Experimental method

X-RAY DIFFRACTION (2.5 Å)