1NW3
Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | histone methyltransferase DOT1L | polymer | 416 | 47506.2 | 1 | UniProt (Q8TEK3) Pfam (PF08123) | Homo sapiens (human) | |
| 2 | B (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 5 | F (A) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47506.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 649.6 | |
| All* | Total formula weight | 48155.8 |
