1K3A
Structure of the Insulin-like Growth Factor 1 Receptor Kinase
Summary for 1K3A
Entry DOI | 10.2210/pdb1k3a/pdb |
Descriptor | insulin-like growth factor 1 receptor, insulin receptor substrate 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | protein kinase, tyrosine kinase, tyrosine phosphorylation, protein-substrate complex, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P08069 |
Total number of polymer chains | 2 |
Total formula weight | 36514.22 |
Authors | Favelyukis, S.,Till, J.H.,Hubbard, S.R.,Miller, W.T. (deposition date: 2001-10-02, release date: 2001-11-28, Last modification date: 2023-11-15) |
Primary citation | Favelyukis, S.,Till, J.H.,Hubbard, S.R.,Miller, W.T. Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat.Struct.Biol., 8:1058-1063, 2001 Cited by PubMed: 11694888DOI: 10.1038/nsb721 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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