1K3A

Structure of the Insulin-like Growth Factor 1 Receptor Kinase

Summary for 1K3A

Entry DOI	10.2210/pdb1k3a/pdb
Descriptor	insulin-like growth factor 1 receptor, insulin receptor substrate 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	protein kinase, tyrosine kinase, tyrosine phosphorylation, protein-substrate complex, transferase
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P08069
Total number of polymer chains	2
Total formula weight	36514.22
Authors	Favelyukis, S.,Till, J.H.,Hubbard, S.R.,Miller, W.T. (deposition date: 2001-10-02, release date: 2001-11-28, Last modification date: 2023-11-15)
Primary citation	Favelyukis, S.,Till, J.H.,Hubbard, S.R.,Miller, W.T. Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat.Struct.Biol., 8:1058-1063, 2001 Cited by PubMed: 11694888 DOI: 10.1038/nsb721 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation