Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE ACP A 300 |
Chain | Residue |
A | HOH67 |
A | SER979 |
A | VAL983 |
A | ALA1001 |
A | GLU1050 |
A | MET1052 |
A | ASN1110 |
A | MET1112 |
A | ASP1123 |
A | HOH87 |
A | HOH98 |
A | HOH101 |
A | HOH158 |
A | HOH164 |
A | LEU975 |
A | GLN977 |
A | GLY978 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 29 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGSFGMVYeGvakgvvkdepetr.....VAIK |
Chain | Residue | Details |
A | LEU975-LYS1003 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLAARNCMV |
Chain | Residue | Details |
A | PHE1101-VAL1113 | |
site_id | PS00239 |
Number of Residues | 9 |
Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. DIYetdYYR |
Chain | Residue | Details |
A | ASP1129-ARG1137 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS1003 | |
Chain | Residue | Details |
A | PTR1131 | |
A | PTR1135 | |
A | PTR1136 | |
Chain | Residue | Details |
A | SER1248 | |
Chain | Residue | Details |
A | SER1252 | |
site_id | SWS_FT_FI7 |
Number of Residues | 3 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:21994939 |
Chain | Residue | Details |
A | LYS1138 | |
A | LYS1141 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP1105 | |
A | ARG1109 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ALA1107 | |
A | ASP1105 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ALA1107 | |
A | ASP1105 | |
A | ASN1110 | |