1K3A
Structure of the Insulin-like Growth Factor 1 Receptor Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | insulin-like growth factor 1 receptor | polymer | 299 | 34410.2 | 1 | UniProt (P08069) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (B) | insulin receptor substrate 1 | polymer | 14 | 1598.8 | 1 | UniProt (P35568) | IRS-1 | |
| 3 | C (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 958 - 1256 (UniProt: P08069)
B: 3 - 14 (UniProt: P35568)
| PDB | External Database | Details |
|---|---|---|
| Ptr 1131 | Tyr 1161 | modified residue |
| Ptr 1135 | Tyr 1165 | modified residue |
| Ptr 1136 | Tyr 1166 | modified residue |
| Leu 1212 | Phe 1242 | variant |
| PDB | External Database | Details |
|---|---|---|
| Lys 1 | - | SEE REMARK 999 |
| Lys 2 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36009.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 505.2 | |
| All* | Total formula weight | 36514.2 |
