1HD7
A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism
Summary for 1HD7
Entry DOI | 10.2210/pdb1hd7/pdb |
Related | 1BIX 1CQG 1CQH 1DE8 1DE9 1DEW 1E9N |
Descriptor | DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION (3 entities in total) |
Functional Keywords | dna repair, endonuclease, ape1, hap1, ref-1 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695 |
Total number of polymer chains | 1 |
Total formula weight | 35813.69 |
Authors | Beernink, P.T.,Segelke, B.W.,Rupp, B. (deposition date: 2000-11-09, release date: 2001-02-16, Last modification date: 2024-05-01) |
Primary citation | Beernink, P.T.,Segelke, B.W.,Hadi, M.Z.,Erzberger, J.P.,Wilson III, D.M.,Rupp, B. Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307:1023-, 2001 Cited by PubMed: 11286553DOI: 10.1006/JMBI.2001.4529 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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