1FQ5

X-ray structure of a cyclic statine inhibitor PD-129,541 bound to yeast proteinase A

Summary for 1FQ5

Entry DOI	10.2210/pdb1fq5/pdb
Related	1dpj 1fq4 1fq6 1fq7 1fq8 2jxr
Descriptor	SACCHAROPEPSIN, beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Saccharomyces cerevisiae (baker's yeast)
Total number of polymer chains	1
Total formula weight	37746.64
Authors	Cronin, N.B.,Badasso, M.O.,Tickle, I.J.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B. (deposition date: 2000-09-03, release date: 2000-09-20, Last modification date: 2020-07-29)
Primary citation	Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity. J.Mol.Biol., 303:745-760, 2000 Cited by PubMed: 11061973 DOI: 10.1006/jmbi.2000.4181 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation