1FQ6
X-RAY STRUCTURE OF GLYCOL INHIBITOR PD-133,450 BOUND TO SACCHAROPEPSIN
Summary for 1FQ6
Entry DOI | 10.2210/pdb1fq6/pdb |
Related | 1dp5 1fq4 1fq5 1fq7 1fq8 2jxr |
Related PRD ID | PRD_000356 |
Descriptor | SACCHAROPEPSIN, alpha-L-gulopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(1S)-2-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino}-1-(ethylsulfanyl)-2-oxoethyl]-Nalpha-(morp holin-4-ylsulfonyl)-L-phenylalaninamide, ... (5 entities in total) |
Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Total number of polymer chains | 1 |
Total formula weight | 37563.48 |
Authors | Cronin, N.B.,Badasso, M.O.,Tickle, I.J.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B. (deposition date: 2000-09-03, release date: 2000-09-20, Last modification date: 2020-07-29) |
Primary citation | Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity. J.Mol.Biol., 303:745-760, 2000 Cited by PubMed: 11061973DOI: 10.1006/jmbi.2000.4181 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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