1FQ5
X-ray structure of a cyclic statine inhibitor PD-129,541 bound to yeast proteinase A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SACCHAROPEPSIN | polymer | 329 | 35774.6 | 1 | UniProt (P07267) Pfam (PF00026) In PDB | Saccharomyces cerevisiae (baker's yeast) | ASPARTATE PROTEASE, PROTEINASE A |
2 | B | beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G28438DM) | |||
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | A | N-[(5S,9S,10S,13S)-9-hydroxy-5,10-bis(2-methylpropyl)-4,7,12,16-tetraoxo-3,6,11,17-tetraazabicyclo[17.3.1]tricosa-1(23),19,21-trien-13-yl]-3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamide | non-polymer | 840.1 | 1 | Chemie (0GM) | |||
5 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 0 - 326 (UniProt: P07267)
PDB | External Database | Details |
---|---|---|
Ile 315 | Leu 394 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35774.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 910.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1061.3 | |
All* | Total formula weight | 37746.6 |