1E2F
Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate and a magnesium-ion
Summary for 1E2F
Entry DOI | 10.2210/pdb1e2f/pdb |
Related | 1E2D 1E2E 1E2G 1E2Q 1E98 1E99 1E9A 1E9B 1E9C 1E9D 1E9E 1E9F 1NMX 1NMY 1NMZ 1NN0 1NN1 1NN3 1NN5 2XX3 |
Descriptor | THYMIDYLATE KINASE, THYMIDINE-5'-PHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total) |
Functional Keywords | transferase, treansferase, p-loop |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 25356.75 |
Authors | Ostermann, N.,Schlichting, I.,Brundiers, R.,Konrad, M.,Reinstein, J.,Veit, T.,Goody, R.S.,Lavie, A. (deposition date: 2000-05-22, release date: 2001-05-17, Last modification date: 2019-07-24) |
Primary citation | Ostermann, N.,Schlichting, I.,Brundiers, R.,Konrad, M.,Reinstein, J.,Veit, T.,Goody, R.S.,Lavie, A. Insights Into the Phosphoryltransfer Mechanism of Human Thymidylate Kinase Gained from Crystal Structures of Enzyme Complexes Along the Reaction Coordinate Structure, 8:629-, 2000 Cited by PubMed: 10873853DOI: 10.1016/S0969-2126(00)00149-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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