1NN0

Crystal structure of human thymidylate kinase with ddTMP and ADP

Summary for 1NN0
DescriptorThymidylate kinase, MAGNESIUM ION, 3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ... (5 entities in total)
Functional Keywordsthymidylate kinase, p-loop, dideoxythymidine, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight24834.55
Authors
Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. (deposition date: 2003-01-12, release date: 2003-03-18, Last modification date: 2017-10-11)
Primary citationKonrad, M.,Lavie, A.,Meier, C.,Monnerjahn, M.,Ostermann, N.,Segura-Pena, D.,Veit, T.
Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds
Biochemistry, 42:2568-2577, 2003
PubMed: 12614151
DOI: 110.1021/bi027302t
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation
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178938

PDB entries from 2021-06-16