1XFA
Structure of NBD1 from murine CFTR- F508R mutant
Summary for 1XFA
Entry DOI | 10.2210/pdb1xfa/pdb |
Related | 1XF9 |
Descriptor | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | cystic fibrosis, abc transporters, atp, nucleotide-binding domain, transport protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Early endosome membrane; Multi-pass membrane protein (By similarity): P26361 |
Total number of polymer chains | 2 |
Total formula weight | 64932.17 |
Authors | Thibodeau, P.H.,Brautigam, C.A.,Machius, M.,Thomas, P.J. (deposition date: 2004-09-14, release date: 2004-12-28, Last modification date: 2023-08-23) |
Primary citation | Thibodeau, P.H.,Brautigam, C.A.,Machius, M.,Thomas, P.J. Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol., 12:10-16, 2005 Cited by PubMed: 15619636DOI: 10.1038/nsmb881 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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