1OC0

plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin

Summary for 1OC0

Entry DOI	10.2210/pdb1oc0/pdb
Related	1A7C 1B3K 1C5G 1DB2 1DVM 1DVN 1LJ5 9PAI
Descriptor	PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN (3 entities in total)
Functional Keywords	hydrolase-inhibitor complex, serine protease inhibitor-complex, serpin, proteinase inhibitor, fibrinolysis, cell migration, plasminogen activation, heparin-binding, cell adhesion, hydrolase/inhibitor
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P05121 Secreted, extracellular space: P04004
Total number of polymer chains	2
Total formula weight	48606.52
Authors	Read, R.J.,Zhou, A.,Huntington, J.A.,Pannu, N.S.,Carrell, R.W. (deposition date: 2003-02-03, release date: 2003-06-19, Last modification date: 2023-12-13)
Primary citation	Zhou, A.,Huntington, J.A.,Pannu, N.S.,Carrell, R.W.,Read, R.J. How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration Nat.Struct.Biol., 10:541-, 2003 Cited by PubMed: 12808446 DOI: 10.1038/NSB943 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.28 Å)

Structure validation