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1CZA

MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE, GLUCOSE-6-PHOSPHATE, AND ADP

Summary for 1CZA
Entry DOI10.2210/pdb1cza/pdb
Related1HKB 1HKC
DescriptorHEXOKINASE TYPE I, alpha-D-glucopyranose, 6-O-phosphono-alpha-D-glucopyranose, ... (5 entities in total)
Functional Keywordsstructurally homologous domains, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight103894.79
Authors
Aleshin, A.E.,Liu, X.,Kirby, C.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1999-09-01, release date: 2000-03-06, Last modification date: 2024-02-07)
Primary citationAleshin, A.E.,Kirby, C.,Liu, X.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B.
Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296:1001-1015, 2000
Cited by
PubMed: 10686099
DOI: 10.1006/jmbi.1999.3494
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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