Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1C8T

HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812

Summary for 1C8T
Entry DOI10.2210/pdb1c8t/pdb
Related1C3I 1HFS 1SLM
DescriptorSTROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywordsprotein-inhibitor complex, mutant protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space, extracellular matrix (Probable): P08254
Total number of polymer chains2
Total formula weight38802.83
Authors
Steele, D.L.,el-Kabbani, O.,Dunten, P.,Crowther, R.L. (deposition date: 1999-07-29, release date: 2000-07-19, Last modification date: 2024-03-13)
Primary citationSteele, D.L.,El-Kabbani, O.,Dunten, P.,Windsor, L.J.,Kammlott, R.U.,Crowther, R.L.,Michoud, C.,Engler, J.A.,Birktoft, J.J.
Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.
Protein Eng., 13:397-405, 2000
Cited by
PubMed: 10877850
DOI: 10.1093/protein/13.6.397
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon