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9C2C

Cryo-EM structure of the human P2X1 receptor in the NF449-bound inhibited state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, C, B)
P2X purinoceptor 1polymer39945039.03UniProt (P51575)
Pfam (PF00864)
Homo sapiens (human)P2X1,ATP receptor,Purinergic receptor
2D, E, H, I, J...
(A, C, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.29Chemie (NAG)
3F, G, K, L, P...
(A, C, B)
4,4',4'',4'''-{carbonylbis[azanediylbenzene-5,1,3-triylbis(carbonylazanediyl)]}tetra(benzene-1,3-disulfonic acid)non-polymer1329.26Chemie (A1ALI)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight135116.9
Non-Polymers*Number of molecules15
Total formula weight9966.3
All*Total formula weight145083.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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