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8X3S

Crystal structure of human WDR5 in complex with PTEN

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 5polymer31434478.11UniProt (P61964)
Pfam (PF00400)
Homo sapiens (human)
2B
(B)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENpolymer343466.81UniProt (P60484)Homo sapiens (human)Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog
3C, D
(A, B)
waterwater18.0125Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37944.8
All*Total formula weight37944.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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