8U4R
Structure of REGN7663-Fab bound CXCR4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | REGN7663 Fab light chain | polymer | 219 | 24185.9 | 1 | Homo sapiens (human) | ||
2 | H | REGN7663 Fab heavy chain | polymer | 240 | 25799.9 | 1 | Homo sapiens (human) | ||
3 | R | C-X-C chemokine receptor type 4 | polymer | 632 | 71063.6 | 1 | UniProt (P61073) Pfam (PF12109) Pfam (PF00001) Pfam (PF01353) UniProt (by SIFTS) (P42212) In PDB | Homo sapiens (human) | |
4 | R | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
R: 2 - 352 (UniProt: P61073)
R: 353 - 614 (PDB: 8U4R)
PDB | External Database | Details |
---|---|---|
Met -17 | - | initiating methionine |
Lys -16 | - | expression tag |
Thr -15 | - | expression tag |
Ile -14 | - | expression tag |
Ile -13 | - | expression tag |
Ala -12 | - | expression tag |
Leu -11 | - | expression tag |
Ser -10 | - | expression tag |
Tyr -9 | - | expression tag |
Ile -8 | - | expression tag |
Phe -7 | - | expression tag |
Cys -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Phe -3 | - | expression tag |
Ala -2 | - | expression tag |
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Pro 1 | - | expression tag |
Ser 119 | Asn 119 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 121049.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 386.7 | |
All* | Total formula weight | 121436.1 |