8TT8
Joint Xray/Neutron structure of Macrophage Migration Inhibitory Factor (MIF) Bound to 4-hydroxyphenylpyruvate at room temperature
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | D, E (A, B) | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID | non-polymer | 180.2 | 2 | Chemie (ENO) | |||
| 3 | F (B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | G (C) | (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid | non-polymer | 180.2 | 1 | Chemie (EN1) | |||
| 5 | H, I, J (A, B, C) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37065.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 600.6 | |
| All* | Total formula weight | 37665.7 |
