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8TT8

Joint Xray/Neutron structure of Macrophage Migration Inhibitory Factor (MIF) Bound to 4-hydroxyphenylpyruvate at room temperature

Summary for 8TT8
Entry DOI10.2210/pdb8tt8/pdb
Related1CA7 3IJJ 8TT9
DescriptorMacrophage migration inhibitory factor, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ISOPROPYL ALCOHOL, ... (5 entities in total)
Functional Keywordsmacrophage migration inhibitory factor, cytokine
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total formula weight37665.73
Authors
Schroder, G.C.,Meilleur, F.,Crichlow, G.V.,Lolis, E.J. (deposition date: 2023-08-13, release date: 2025-08-27)
Primary citationSchroder, G.C.,Crichlow, G.V.,Zambrzycka, E.,Pantouris, G.,Nix, J.,Chayen, N.,Meilleur, F.,Lolis, E.J.
Joint Xray/Neutron structure of Macrophage Migration Inhibitory Factor (MIF) Bound to 4-hydroxyphenylpyruvate at room temperature
To Be Published,
Experimental method
NEUTRON DIFFRACTION (2.53 Å)
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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