8SPN
Crystal structure of macrophage migration inhibitory factor in complex with T614
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | D, H (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | E (B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | F (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G (C) | Iguratimod | non-polymer | 374.4 | 1 | Chemie (7TN) | |||
| 6 | I, J, K (A, B, C) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37065.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 718.7 | |
| All* | Total formula weight | 37783.9 |
