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8QZZ

Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Eukaryotic translation initiation factor 2 subunit 3polymer47251178.41UniProt (P41091)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF09173)
Homo sapiens (human)Eukaryotic translation initiation factor 2 subunit gamma X,eIF-2gX
2B
(B)
Eukaryotic translation initiation factor 2 subunit 1polymer31536161.21UniProt (P05198)
Pfam (PF00575)
Pfam (PF07541)
Homo sapiens (human)Eukaryotic translation initiation factor 2 subunit alpha,eIF-2alpha
3C
(C)
Protein phosphatase 1 regulatory subunit 15Apolymer333687.71UniProt (O75807)Homo sapiens (human)Growth arrest and DNA damage-inducible protein GADD34,Myeloid differentiation primary response protein MyD116 homolog
4D
(A)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight91027.3
Non-Polymers*Number of molecules1
Total formula weight522.2
All*Total formula weight91549.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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