8P94
Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-related protein 3 | polymer | 418 | 47428.0 | 1 | UniProt (P61158) Pfam (PF00022) | Homo sapiens (human) | Actin-like protein 3 |
| 2 | B (B) | Actin-related protein 2 | polymer | 394 | 44818.7 | 1 | UniProt (P61160) Pfam (PF00022) | Homo sapiens (human) | Actin-like protein 2 |
| 3 | C (C) | Actin-related protein 2/3 complex subunit 1B | polymer | 372 | 41004.8 | 1 | UniProt (O15143) Pfam (PF00400) | Homo sapiens (human) | Arp2/3 complex 41 kDa subunit,p41-ARC |
| 4 | D (D) | Actin-related protein 2/3 complex subunit 2 | polymer | 300 | 34386.0 | 1 | UniProt (O15144) Pfam (PF04045) | Homo sapiens (human) | Arp2/3 complex 34 kDa subunit,p34-ARC |
| 5 | E (E) | Actin-related protein 2/3 complex subunit 3 | polymer | 178 | 20572.7 | 1 | UniProt (O15145) Pfam (PF04062) | Homo sapiens (human) | Arp2/3 complex 21 kDa subunit,p21-ARC |
| 6 | F (F) | Actin-related protein 2/3 complex subunit 4 | polymer | 168 | 19697.0 | 1 | UniProt (P59998) Pfam (PF05856) | Homo sapiens (human) | Arp2/3 complex 20 kDa subunit,p20-ARC |
| 7 | G (G) | Actin-related protein 2/3 complex subunit 5-like protein | polymer | 153 | 16964.2 | 1 | UniProt (Q9BPX5) Pfam (PF04699) | Homo sapiens (human) | Arp2/3 complex 16 kDa subunit 2,ARC16-2 |
| 8 | H, J, K, L, M... (H, J, K, N, O...) | Actin, cytoplasmic 1 | polymer | 375 | 41782.7 | 10 | UniProt (Q6QAQ1) Pfam (PF00022) | Sus scrofa (pig) | Beta-actin |
| 9 | I (I) | Src substrate cortactin | polymer | 546 | 61340.7 | 1 | UniProt (Q60598) Pfam (PF02218) Pfam (PF14604) | Mus musculus (house mouse) | |
| 10 | R (U) | F-actin-capping protein subunit alpha-1 | polymer | 286 | 32980.7 | 1 | UniProt (P47753) Pfam (PF01267) | Mus musculus (house mouse) | CapZ alpha-1 |
| 11 | S (V) | Isoform 2 of F-actin-capping protein subunit beta | polymer | 272 | 30669.8 | 1 | UniProt (P47757) Pfam (PF01115) | Mus musculus (house mouse) | CapZ beta |
| 12 | AA, BA, CA, DA, U... (a, b, c, d, h...) | Phalloidin | polymer | 7 | 808.9 | 10 | BIRD (PRD_002366) | Amanita phalloides | |
| 13 | AB, EA, GA, IA, KA... (W, A, B, H, J...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 12 | Chemie (ADP) | |||
| 14 | BB, FA, HA, JA, LA... (W, A, B, H, J...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 775778.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5418.1 | |
| All* | Total formula weight | 781196.3 |
