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8P94

Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0003779molecular_functionactin binding
A0005200molecular_functionstructural constituent of cytoskeleton
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005885cellular_componentArp2/3 protein complex
A0005903cellular_componentbrush border
A0005911cellular_componentcell-cell junction
A0005925cellular_componentfocal adhesion
A0007163biological_processestablishment or maintenance of cell polarity
A0008356biological_processasymmetric cell division
A0010592biological_processpositive regulation of lamellipodium assembly
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0016344biological_processmeiotic chromosome movement towards spindle pole
A0030027cellular_componentlamellipodium
A0030030biological_processcell projection organization
A0033206biological_processmeiotic cytokinesis
A0034314biological_processArp2/3 complex-mediated actin nucleation
A0035861cellular_componentsite of double-strand break
A0042995cellular_componentcell projection
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0051015molecular_functionactin filament binding
A0051321biological_processmeiotic cell cycle
A0051653biological_processspindle localization
A0060271biological_processcilium assembly
A0070062cellular_componentextracellular exosome
A0070358biological_processactin polymerization-dependent cell motility
A0071346biological_processcellular response to type II interferon
B0003779molecular_functionactin binding
B0005200molecular_functionstructural constituent of cytoskeleton
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005885cellular_componentArp2/3 protein complex
B0005925cellular_componentfocal adhesion
B0005938cellular_componentcell cortex
B0007163biological_processestablishment or maintenance of cell polarity
B0008356biological_processasymmetric cell division
B0010592biological_processpositive regulation of lamellipodium assembly
B0015629cellular_componentactin cytoskeleton
B0016020cellular_componentmembrane
B0016344biological_processmeiotic chromosome movement towards spindle pole
B0016482biological_processcytosolic transport
B0030036biological_processactin cytoskeleton organization
B0030478cellular_componentactin cap
B0033206biological_processmeiotic cytokinesis
B0034314biological_processArp2/3 complex-mediated actin nucleation
B0035578cellular_componentazurophil granule lumen
B0035861cellular_componentsite of double-strand break
B0042995cellular_componentcell projection
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0051015molecular_functionactin filament binding
B0051321biological_processmeiotic cell cycle
B0051653biological_processspindle localization
B0060271biological_processcilium assembly
B0070062cellular_componentextracellular exosome
B0071346biological_processcellular response to type II interferon
B1904813cellular_componentficolin-1-rich granule lumen
B1905168biological_processpositive regulation of double-strand break repair via homologous recombination
B2001032biological_processregulation of double-strand break repair via nonhomologous end joining
C0003779molecular_functionactin binding
C0005200molecular_functionstructural constituent of cytoskeleton
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005885cellular_componentArp2/3 protein complex
C0005925cellular_componentfocal adhesion
C0015629cellular_componentactin cytoskeleton
C0032355biological_processresponse to estradiol
C0034314biological_processArp2/3 complex-mediated actin nucleation
C0036284cellular_componenttubulobulbar complex
C0043627biological_processresponse to estrogen
C0044877molecular_functionprotein-containing complex binding
C0051015molecular_functionactin filament binding
C0070062cellular_componentextracellular exosome
D0003779molecular_functionactin binding
D0005200molecular_functionstructural constituent of cytoskeleton
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005768cellular_componentendosome
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005885cellular_componentArp2/3 protein complex
D0005886cellular_componentplasma membrane
D0005925cellular_componentfocal adhesion
D0010592biological_processpositive regulation of lamellipodium assembly
D0015629cellular_componentactin cytoskeleton
D0030027cellular_componentlamellipodium
D0030041biological_processactin filament polymerization
D0030672cellular_componentsynaptic vesicle membrane
D0030838biological_processpositive regulation of actin filament polymerization
D0031252cellular_componentcell leading edge
D0034314biological_processArp2/3 complex-mediated actin nucleation
D0035861cellular_componentsite of double-strand break
D0036195cellular_componentmuscle cell projection membrane
D0042995cellular_componentcell projection
D0043005cellular_componentneuron projection
D0045202cellular_componentsynapse
D0051015molecular_functionactin filament binding
D0070062cellular_componentextracellular exosome
D0070358biological_processactin polymerization-dependent cell motility
D0098793cellular_componentpresynapse
D0098794cellular_componentpostsynapse
D0098978cellular_componentglutamatergic synapse
D1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
E0003779molecular_functionactin binding
E0005200molecular_functionstructural constituent of cytoskeleton
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005885cellular_componentArp2/3 protein complex
E0005925cellular_componentfocal adhesion
E0015629cellular_componentactin cytoskeleton
E0016020cellular_componentmembrane
E0030027cellular_componentlamellipodium
E0030833biological_processregulation of actin filament polymerization
E0031252cellular_componentcell leading edge
E0031941cellular_componentfilamentous actin
E0034314biological_processArp2/3 complex-mediated actin nucleation
E0035861cellular_componentsite of double-strand break
E0042995cellular_componentcell projection
E0051015molecular_functionactin filament binding
E0061850cellular_componentgrowth cone leading edge
E0070062cellular_componentextracellular exosome
E0070358biological_processactin polymerization-dependent cell motility
E1900242biological_processregulation of synaptic vesicle endocytosis
E1990090biological_processcellular response to nerve growth factor stimulus
F0003779molecular_functionactin binding
F0005200molecular_functionstructural constituent of cytoskeleton
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005885cellular_componentArp2/3 protein complex
F0015629cellular_componentactin cytoskeleton
F0019899molecular_functionenzyme binding
F0030041biological_processactin filament polymerization
F0030674molecular_functionprotein-macromolecule adaptor activity
F0034314biological_processArp2/3 complex-mediated actin nucleation
F0035861cellular_componentsite of double-strand break
F0042995cellular_componentcell projection
F0045010biological_processactin nucleation
F0051015molecular_functionactin filament binding
F0070062cellular_componentextracellular exosome
G0003674molecular_functionmolecular_function
G0003779molecular_functionactin binding
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005856cellular_componentcytoskeleton
G0005885cellular_componentArp2/3 protein complex
G0005925cellular_componentfocal adhesion
G0008150biological_processbiological_process
G0015629cellular_componentactin cytoskeleton
G0016477biological_processcell migration
G0030833biological_processregulation of actin filament polymerization
G0034314biological_processArp2/3 complex-mediated actin nucleation
G0045202cellular_componentsynapse
G0051015molecular_functionactin filament binding
G0070062cellular_componentextracellular exosome
G0098978cellular_componentglutamatergic synapse
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0005856cellular_componentcytoskeleton
H0005884cellular_componentactin filament
H0005886cellular_componentplasma membrane
H0005925cellular_componentfocal adhesion
H0007409biological_processaxonogenesis
H0015629cellular_componentactin cytoskeleton
H0016020cellular_componentmembrane
H0016787molecular_functionhydrolase activity
H0019901molecular_functionprotein kinase binding
H0030424cellular_componentaxon
H0032991cellular_componentprotein-containing complex
H0035267cellular_componentNuA4 histone acetyltransferase complex
H0045202cellular_componentsynapse
H0048870biological_processcell motility
H0097433cellular_componentdense body
H0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
H0098974biological_processpostsynaptic actin cytoskeleton organization
I0001726cellular_componentruffle
I0002102cellular_componentpodosome
I0005515molecular_functionprotein binding
I0005522molecular_functionprofilin binding
I0005737cellular_componentcytoplasm
I0005783cellular_componentendoplasmic reticulum
I0005794cellular_componentGolgi apparatus
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005884cellular_componentactin filament
I0005886cellular_componentplasma membrane
I0005905cellular_componentclathrin-coated pit
I0005925cellular_componentfocal adhesion
I0005938cellular_componentcell cortex
I0006886biological_processintracellular protein transport
I0006897biological_processendocytosis
I0006898biological_processreceptor-mediated endocytosis
I0006930biological_processsubstrate-dependent cell migration, cell extension
I0008076cellular_componentvoltage-gated potassium channel complex
I0030027cellular_componentlamellipodium
I0030036biological_processactin cytoskeleton organization
I0030054cellular_componentcell junction
I0030425cellular_componentdendrite
I0030426cellular_componentgrowth cone
I0030516biological_processregulation of axon extension
I0030838biological_processpositive regulation of actin filament polymerization
I0030863cellular_componentcortical cytoskeleton
I0042995cellular_componentcell projection
I0043197cellular_componentdendritic spine
I0043231cellular_componentintracellular membrane-bounded organelle
I0045202cellular_componentsynapse
I0045987biological_processpositive regulation of smooth muscle contraction
I0048041biological_processfocal adhesion assembly
I0048812biological_processneuron projection morphogenesis
I0048870biological_processcell motility
I0070161cellular_componentanchoring junction
I0097062biological_processdendritic spine maintenance
I0097191biological_processextrinsic apoptotic signaling pathway
I0097581biological_processlamellipodium organization
I1901524biological_processregulation of mitophagy
I1990023cellular_componentmitotic spindle midzone
I2001237biological_processnegative regulation of extrinsic apoptotic signaling pathway
J0005515molecular_functionprotein binding
J0005524molecular_functionATP binding
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0005856cellular_componentcytoskeleton
J0005884cellular_componentactin filament
J0005886cellular_componentplasma membrane
J0005925cellular_componentfocal adhesion
J0007409biological_processaxonogenesis
J0015629cellular_componentactin cytoskeleton
J0016020cellular_componentmembrane
J0016787molecular_functionhydrolase activity
J0019901molecular_functionprotein kinase binding
J0030424cellular_componentaxon
J0032991cellular_componentprotein-containing complex
J0035267cellular_componentNuA4 histone acetyltransferase complex
J0045202cellular_componentsynapse
J0048870biological_processcell motility
J0097433cellular_componentdense body
J0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
J0098974biological_processpostsynaptic actin cytoskeleton organization
K0005515molecular_functionprotein binding
K0005524molecular_functionATP binding
K0005634cellular_componentnucleus
K0005737cellular_componentcytoplasm
K0005856cellular_componentcytoskeleton
K0005884cellular_componentactin filament
K0005886cellular_componentplasma membrane
K0005925cellular_componentfocal adhesion
K0007409biological_processaxonogenesis
K0015629cellular_componentactin cytoskeleton
K0016020cellular_componentmembrane
K0016787molecular_functionhydrolase activity
K0019901molecular_functionprotein kinase binding
K0030424cellular_componentaxon
K0032991cellular_componentprotein-containing complex
K0035267cellular_componentNuA4 histone acetyltransferase complex
K0045202cellular_componentsynapse
K0048870biological_processcell motility
K0097433cellular_componentdense body
K0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
K0098974biological_processpostsynaptic actin cytoskeleton organization
N0005515molecular_functionprotein binding
N0005524molecular_functionATP binding
N0005634cellular_componentnucleus
N0005737cellular_componentcytoplasm
N0005856cellular_componentcytoskeleton
N0005884cellular_componentactin filament
N0005886cellular_componentplasma membrane
N0005925cellular_componentfocal adhesion
N0007409biological_processaxonogenesis
N0015629cellular_componentactin cytoskeleton
N0016020cellular_componentmembrane
N0016787molecular_functionhydrolase activity
N0019901molecular_functionprotein kinase binding
N0030424cellular_componentaxon
N0032991cellular_componentprotein-containing complex
N0035267cellular_componentNuA4 histone acetyltransferase complex
N0045202cellular_componentsynapse
N0048870biological_processcell motility
N0097433cellular_componentdense body
N0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
N0098974biological_processpostsynaptic actin cytoskeleton organization
O0005515molecular_functionprotein binding
O0005524molecular_functionATP binding
O0005634cellular_componentnucleus
O0005737cellular_componentcytoplasm
O0005856cellular_componentcytoskeleton
O0005884cellular_componentactin filament
O0005886cellular_componentplasma membrane
O0005925cellular_componentfocal adhesion
O0007409biological_processaxonogenesis
O0015629cellular_componentactin cytoskeleton
O0016020cellular_componentmembrane
O0016787molecular_functionhydrolase activity
O0019901molecular_functionprotein kinase binding
O0030424cellular_componentaxon
O0032991cellular_componentprotein-containing complex
O0035267cellular_componentNuA4 histone acetyltransferase complex
O0045202cellular_componentsynapse
O0048870biological_processcell motility
O0097433cellular_componentdense body
O0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
O0098974biological_processpostsynaptic actin cytoskeleton organization
P0005515molecular_functionprotein binding
P0005524molecular_functionATP binding
P0005634cellular_componentnucleus
P0005737cellular_componentcytoplasm
P0005856cellular_componentcytoskeleton
P0005884cellular_componentactin filament
P0005886cellular_componentplasma membrane
P0005925cellular_componentfocal adhesion
P0007409biological_processaxonogenesis
P0015629cellular_componentactin cytoskeleton
P0016020cellular_componentmembrane
P0016787molecular_functionhydrolase activity
P0019901molecular_functionprotein kinase binding
P0030424cellular_componentaxon
P0032991cellular_componentprotein-containing complex
P0035267cellular_componentNuA4 histone acetyltransferase complex
P0045202cellular_componentsynapse
P0048870biological_processcell motility
P0097433cellular_componentdense body
P0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
P0098974biological_processpostsynaptic actin cytoskeleton organization
Q0005515molecular_functionprotein binding
Q0005524molecular_functionATP binding
Q0005634cellular_componentnucleus
Q0005737cellular_componentcytoplasm
Q0005856cellular_componentcytoskeleton
Q0005884cellular_componentactin filament
Q0005886cellular_componentplasma membrane
Q0005925cellular_componentfocal adhesion
Q0007409biological_processaxonogenesis
Q0015629cellular_componentactin cytoskeleton
Q0016020cellular_componentmembrane
Q0016787molecular_functionhydrolase activity
Q0019901molecular_functionprotein kinase binding
Q0030424cellular_componentaxon
Q0032991cellular_componentprotein-containing complex
Q0035267cellular_componentNuA4 histone acetyltransferase complex
Q0045202cellular_componentsynapse
Q0048870biological_processcell motility
Q0097433cellular_componentdense body
Q0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
Q0098974biological_processpostsynaptic actin cytoskeleton organization
R0005515molecular_functionprotein binding
R0005524molecular_functionATP binding
R0005634cellular_componentnucleus
R0005737cellular_componentcytoplasm
R0005856cellular_componentcytoskeleton
R0005884cellular_componentactin filament
R0005886cellular_componentplasma membrane
R0005925cellular_componentfocal adhesion
R0007409biological_processaxonogenesis
R0015629cellular_componentactin cytoskeleton
R0016020cellular_componentmembrane
R0016787molecular_functionhydrolase activity
R0019901molecular_functionprotein kinase binding
R0030424cellular_componentaxon
R0032991cellular_componentprotein-containing complex
R0035267cellular_componentNuA4 histone acetyltransferase complex
R0045202cellular_componentsynapse
R0048870biological_processcell motility
R0097433cellular_componentdense body
R0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
R0098974biological_processpostsynaptic actin cytoskeleton organization
S0005515molecular_functionprotein binding
S0005524molecular_functionATP binding
S0005634cellular_componentnucleus
S0005737cellular_componentcytoplasm
S0005856cellular_componentcytoskeleton
S0005884cellular_componentactin filament
S0005886cellular_componentplasma membrane
S0005925cellular_componentfocal adhesion
S0007409biological_processaxonogenesis
S0015629cellular_componentactin cytoskeleton
S0016020cellular_componentmembrane
S0016787molecular_functionhydrolase activity
S0019901molecular_functionprotein kinase binding
S0030424cellular_componentaxon
S0032991cellular_componentprotein-containing complex
S0035267cellular_componentNuA4 histone acetyltransferase complex
S0045202cellular_componentsynapse
S0048870biological_processcell motility
S0097433cellular_componentdense body
S0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
S0098974biological_processpostsynaptic actin cytoskeleton organization
U0003779molecular_functionactin binding
U0005515molecular_functionprotein binding
U0005737cellular_componentcytoplasm
U0005829cellular_componentcytosol
U0005856cellular_componentcytoskeleton
U0005903cellular_componentbrush border
U0005911cellular_componentcell-cell junction
U0008290cellular_componentF-actin capping protein complex
U0016020cellular_componentmembrane
U0030863cellular_componentcortical cytoskeleton
U0034329biological_processcell junction assembly
U0051015molecular_functionactin filament binding
U0051016biological_processbarbed-end actin filament capping
U0051693biological_processactin filament capping
U0071203cellular_componentWASH complex
V0003779molecular_functionactin binding
V0005515molecular_functionprotein binding
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005856cellular_componentcytoskeleton
V0005903cellular_componentbrush border
V0007010biological_processcytoskeleton organization
V0008154biological_processactin polymerization or depolymerization
V0008290cellular_componentF-actin capping protein complex
V0014069cellular_componentpostsynaptic density
V0016020cellular_componentmembrane
V0022604biological_processregulation of cell morphogenesis
V0030017cellular_componentsarcomere
V0030018cellular_componentZ disc
V0030027cellular_componentlamellipodium
V0030030biological_processcell projection organization
V0030032biological_processlamellipodium assembly
V0030036biological_processactin cytoskeleton organization
V0030863cellular_componentcortical cytoskeleton
V0032279cellular_componentasymmetric synapse
V0033150cellular_componentcytoskeletal calyx
V0051016biological_processbarbed-end actin filament capping
V0051693biological_processactin filament capping
V0071203cellular_componentWASH complex
V0098685cellular_componentSchaffer collateral - CA1 synapse
V0098686cellular_componenthippocampal mossy fiber to CA3 synapse
V0120212cellular_componentsperm head-tail coupling apparatus
W0005515molecular_functionprotein binding
W0005524molecular_functionATP binding
W0005634cellular_componentnucleus
W0005737cellular_componentcytoplasm
W0005856cellular_componentcytoskeleton
W0005884cellular_componentactin filament
W0005886cellular_componentplasma membrane
W0005925cellular_componentfocal adhesion
W0007409biological_processaxonogenesis
W0015629cellular_componentactin cytoskeleton
W0016020cellular_componentmembrane
W0016787molecular_functionhydrolase activity
W0019901molecular_functionprotein kinase binding
W0030424cellular_componentaxon
W0032991cellular_componentprotein-containing complex
W0035267cellular_componentNuA4 histone acetyltransferase complex
W0045202cellular_componentsynapse
W0048870biological_processcell motility
W0097433cellular_componentdense body
W0098973molecular_functionstructural constituent of postsynaptic actin cytoskeleton
W0098974biological_processpostsynaptic actin cytoskeleton organization
Functional Information from PROSITE/UniProt
site_idPS00231
Number of Residues6
DetailsF_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD
ChainResidueDetails
VCYS62-ASP67

site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
HTYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WISKqEYDE
ChainResidueDetails
HTRP356-GLU364

site_idPS00748
Number of Residues9
DetailsF_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV
ChainResidueDetails
UVAL196-VAL204

site_idPS00749
Number of Residues11
DetailsF_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR
ChainResidueDetails
ULYS256-ARG266

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEPpMNPtkNR
ChainResidueDetails
BLEU108-ARG120
ALEU111-ARG123
HLEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P47756
ChainResidueDetails
VSER2
WMET1
VVAL263
ILYS161
ILYS198
ILYS272
ILYS346
QMET1
RMET1
SMET1

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337
ChainResidueDetails
VLYS235
WASP2
ILYS152
ILYS171
ILYS193
ILYS314
PASP2
QASP2
RASP2
SASP2

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337
ChainResidueDetails
ULYS19
OMET47
PMET44
PMET47
QMET44
QMET47
RMET44
RMET47
SMET44
SMET47
WMET44
ISER418
WMET47
JMET44
JMET47
KMET44
KMET47
NMET44
NMET47
OMET44

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P52907
ChainResidueDetails
ULYS97
WHIS73
JHIS73
KHIS73
NHIS73
OHIS73
PHIS73
QHIS73
RHIS73
SHIS73

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:23806337
ChainResidueDetails
ILYS144
WLYS84
ILYS295
KLYS84
NLYS84
OLYS84
PLYS84
QLYS84
RLYS84
SLYS84

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q14247
ChainResidueDetails
ISER150
ISER261
ISER417
ISER443

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:31600191, ECO:0007744|PubMed:23806337
ChainResidueDetails
ILYS181

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:31600191, ECO:0007744|PubMed:23806337
ChainResidueDetails
ILYS235
ILYS309

site_idSWS_FT_FI9
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q14247
ChainResidueDetails
ILYS304

site_idSWS_FT_FI10
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079
ChainResidueDetails
ITHR401

site_idSWS_FT_FI11
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079
ChainResidueDetails
ISER405
ISER407

site_idSWS_FT_FI12
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q66HL2
ChainResidueDetails
ITYR421

site_idSWS_FT_FI13
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q14247
ChainResidueDetails
ITYR442

site_idSWS_FT_FI14
Number of Residues1
DetailsMOD_RES: Phosphotyrosine; by FAK1 => ECO:0000250|UniProtKB:Q66HL2
ChainResidueDetails
ITYR466

site_idSWS_FT_FI15
Number of Residues2
DetailsMOD_RES: Phosphotyrosine; by SRC => ECO:0000269|PubMed:22252131
ChainResidueDetails
ITYR482
ITYR485

site_idSWS_FT_FI16
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:Q14247
ChainResidueDetails
ILYS144
ILYS181
ILYS295

site_idSWS_FT_FI17
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000250|UniProtKB:Q14247
ChainResidueDetails
ILYS218

225946

PDB entries from 2024-10-09

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