8KG5
Prefusion RSV F Bound to Lonafarnib and D25 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Fusion glycoprotein F0,Fibritin | polymer | 585 | 64530.6 | 3 | UniProt (P03420) UniProt (P10104) Pfam (PF00523) In PDB | Human respiratory syncytial virus A (strain A2) | Collar protein,Whisker antigen control protein |
2 | D | D25 heavy chain | polymer | 231 | 24504.6 | 1 | Homo sapiens (human) | ||
3 | E | D25 light chain | polymer | 214 | 23325.9 | 1 | Homo sapiens (human) | ||
4 | A, B, C | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE | non-polymer | 638.8 | 3 | Chemie (336) |
Sequence modifications
A, B, C: 1 - 513 (UniProt: P03420)
A, B, C: 516 - 543 (UniProt: P10104)
PDB | External Database | Details |
---|---|---|
Ala 102 | Pro 102 | conflict |
Cys 155 | Ser 155 | conflict |
Phe 190 | Ser 190 | conflict |
Leu 207 | Val 207 | conflict |
Cys 290 | Ser 290 | conflict |
Val 379 | Ile 379 | conflict |
Val 447 | Met 447 | conflict |
Gly 514 | - | linker |
Ser 515 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 544 | - | expression tag |
Leu 545 | - | expression tag |
Glu 546 | - | expression tag |
Val 547 | - | expression tag |
Leu 548 | - | expression tag |
Phe 549 | - | expression tag |
Gln 550 | - | expression tag |
Gly 551 | - | expression tag |
Pro 552 | - | expression tag |
Gly 553 | - | expression tag |
Gly 554 | - | expression tag |
Trp 555 | - | expression tag |
Ser 556 | - | expression tag |
His 557 | - | expression tag |
Pro 558 | - | expression tag |
Gln 559 | - | expression tag |
Phe 560 | - | expression tag |
Glu 561 | - | expression tag |
Lys 562 | - | expression tag |
Gly 563 | - | expression tag |
Gly 564 | - | expression tag |
Gly 565 | - | expression tag |
Ser 566 | - | expression tag |
Gly 567 | - | expression tag |
Gly 568 | - | expression tag |
Gly 569 | - | expression tag |
Ser 570 | - | expression tag |
Gly 571 | - | expression tag |
Gly 572 | - | expression tag |
Ser 573 | - | expression tag |
Ala 574 | - | expression tag |
Trp 575 | - | expression tag |
Ser 576 | - | expression tag |
His 577 | - | expression tag |
Pro 578 | - | expression tag |
Gln 579 | - | expression tag |
Phe 580 | - | expression tag |
Glu 581 | - | expression tag |
Lys 582 | - | expression tag |
Gly 583 | - | expression tag |
Gly 584 | - | expression tag |
Ser 585 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 241422.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1916.5 | |
All* | Total formula weight | 243338.8 |