8KG5
Prefusion RSV F Bound to Lonafarnib and D25 Fab
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| D | TYR194-HIS200 | |
| E | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11493675, ECO:0000269|PubMed:12127793 |
| Chain | Residue | Details |
| A | ARG109 | |
| B | ARG109 | |
| C | ARG109 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11369882, ECO:0000269|PubMed:12127793 |
| Chain | Residue | Details |
| A | ARG136 | |
| B | ARG136 | |
| C | ARG136 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636 |
| Chain | Residue | Details |
| A | ASN27 | |
| B | ASN27 | |
| C | ASN27 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033 |
| Chain | Residue | Details |
| A | ASN70 | |
| B | ASN70 | |
| C | ASN70 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN116 | |
| A | ASN120 | |
| A | ASN126 | |
| B | ASN116 | |
| B | ASN120 | |
| B | ASN126 | |
| C | ASN116 | |
| C | ASN120 | |
| C | ASN126 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220 |
| Chain | Residue | Details |
| A | ASN500 | |
| B | ASN500 | |
| C | ASN500 |
