8IYX

Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Probable G-protein coupled receptor 34,Probable G-protein coupled receptor 34,YL-365	polymer	581	66231.8	1	UniProt (Q9UPC5) Pfam (PF00001)	Homo sapiens (human)
2	B (C)	1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid	non-polymer		583.1	1	Chemie (S6R)

Sequence modifications

C: 1 - 242 (UniProt: Q9UPC5)
C: 242 - 250 (PDB: 8IYX)
C: 250 - 381 (UniProt: Q9UPC5)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	66231.8
Non-Polymers*	Number of molecules	1
	Total formula weight	583.1
All*	Total formula weight	66814.9

*Water molecules are not included.