8E2I

Cryo-EM structure of BIRC6/Smac

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Baculoviral IAP repeat-containing protein 6	polymer	4888	534158.3	2	UniProt (Q9NR09) Pfam (PF00653) Pfam (PF12356) Pfam (PF00179)	Homo sapiens (human)	BIR repeat-containing ubiquitin-conjugating enzyme,BRUCE,RING-type E3 ubiquitin transferase BIRC6,Ubiquitin-conjugating BIR domain enzyme apollon,APOLLON
2	C, D (F, E)	Diablo IAP-binding mitochondrial protein	polymer	194	22161.6	2	UniProt (Q9NR28) Pfam (PF09057)	Homo sapiens (human)	Diablo homolog,mitochondrial,Direct IAP-binding protein with low pI,Second mitochondria-derived activator of caspase,Smac
3	E, F (C, D)	Baculoviral IAP repeat-containing protein 6	polymer	57	4869.0	2		Homo sapiens (Human)

Sequence modifications

A, B: 1 - 4857 (UniProt: Q9NR09)

PDB	External Database	Details
Met -30	-	expression tag
Asp -29	-	expression tag
Tyr -28	-	expression tag
Lys -27	-	expression tag
Asp -26	-	expression tag
Asp -25	-	expression tag
Asp -24	-	expression tag
Asp -23	-	expression tag
Lys -22	-	expression tag
Leu -21	-	expression tag
Ala -20	-	expression tag
Ala -19	-	expression tag
Ala -18	-	expression tag
Asn -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Ile -14	-	expression tag
Asp -13	-	expression tag
Leu -12	-	expression tag
Ile -11	-	expression tag
Ser -10	-	expression tag
Thr -9	-	expression tag
Ser -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Lys -4	-	expression tag
Ala -3	-	expression tag
Gly -2	-	expression tag
Leu -1	-	expression tag
Thr 0	-	expression tag
Val 1332	Leu 1332	conflict

F, E: 1 - 184 (UniProt: Q9NR28)

PDB	External Database	Details
Met 0	-	initiating methionine
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	1122377.8
All*	Total formula weight	1122377.8

*Water molecules are not included.