8CN9
Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K, P (A, F, K, P) | Fab light chain | polymer | 214 | 23385.0 | 4 | Homo sapiens | ||
| 2 | B, G, L, Q (B, G, L, Q) | Fab heavy chain | polymer | 220 | 23434.1 | 4 | Homo sapiens | ||
| 3 | C, H, M, R (C, H, M, R) | Coagulation factor VII | polymer | 254 | 28103.3 | 4 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 4 | D, I, N, S (D, I, N, S) | Coagulation factor VII | polymer | 107 | 11671.0 | 4 | UniProt (P08709) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 5 | E, J, O, T (E, J, O, T) | Tissue factor | polymer | 219 | 24826.5 | 4 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (human) | TF,Coagulation factor III,Thromboplastin |
| 6 | BA, CA, DA, FA, GA... (K, M, R, A, C...) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 7 | AA, HA, W (I, S, D) | beta-D-glucopyranose | non-polymer | 180.2 | 3 | Chemie (BGC) | |||
| 8 | EA (P) | CESIUM ION | non-polymer | 132.9 | 1 | Chemie (CS) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 445679.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1074.2 | |
| All* | Total formula weight | 446753.6 |
