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Human IL-27 in complex with neutralizing SRF388 FAb fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Interleukin-27 subunit alpha	polymer	215	24562.2	2	UniProt (Q8NEV9) In PDB	Homo sapiens (human)	IL-27 subunit alpha,IL-27-A,IL27-A,Interleukin-30,p28
2	B, D	Interleukin-27 subunit beta	polymer	209	23338.7	2	UniProt (Q14213) Pfam (PF00041) In PDB	Homo sapiens (human)	IL-27 subunit beta,IL-27B,Epstein-Barr virus-induced gene 3 protein,EBV-induced gene 3 protein
3	H, J	SRF388 Heavy Chain	polymer	229	24235.1	2		Homo sapiens
4	I, L	SRF388 Light Chain	polymer	220	23979.6	2		Homo sapiens
5	B, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6		water	water		18.0	566	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	192231.1
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	192673.5

*Water molecules are not included.