7ZXK
Human IL-27 in complex with neutralizing SRF388 FAb fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Interleukin-27 subunit alpha | polymer | 215 | 24562.2 | 2 | UniProt (Q8NEV9) | Homo sapiens (human) | IL-27 subunit alpha,IL-27-A,IL27-A,Interleukin-30,p28 |
| 2 | B, D (B, D) | Interleukin-27 subunit beta | polymer | 209 | 23338.7 | 2 | UniProt (Q14213) Pfam (PF00041) | Homo sapiens (human) | IL-27 subunit beta,IL-27B,Epstein-Barr virus-induced gene 3 protein,EBV-induced gene 3 protein |
| 3 | E, G (H, J) | SRF388 Heavy Chain | polymer | 229 | 24235.1 | 2 | Homo sapiens | ||
| 4 | F, H (I, L) | SRF388 Light Chain | polymer | 220 | 23979.6 | 2 | Homo sapiens | ||
| 5 | I, J (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | K, L, M, N, O... (A, B, C, D, H...) | water | water | 18.0 | 566 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 192231.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 192673.5 |
