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7ZKX

SRPK2 IN COMPLEX WITH INHIBITOR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SRSF protein kinase 2polymer61970206.61UniProt (P78362)
Pfam (PF00069)
Homo sapiens (human)SFRS protein kinase 2,Serine/arginine-rich protein-specific kinase 2,SR-protein-specific kinase 2
2B
(A)
N-[3-[[[2-(6-chloranyl-5-fluoranyl-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-N-methyl-methanesulfonamidenon-polymer461.91Chemie (IXQ)
3C, D, E, F, M
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
4G, I, J
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5H, K
(A)
NITRATE IONnon-polymer62.02Chemie (NO3)
6L
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
7N
(A)
waterwater18.0133Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight70206.6
Non-Polymers*Number of molecules12
Total formula weight1311.5
All*Total formula weight71518.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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