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7YZE

Crystal structure of the human FoxA2 bound to the TGTTTACT site (forkhead motif GTAAACA)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hepatocyte nuclear factor 3-betapolymer12514652.81UniProt (Q9Y261)
Pfam (PF00250)
Homo sapiens (human)HNF-3-beta,HNF-3B,Forkhead box protein A2,Transcription factor 3B,TCF-3B
2B
(B)
DNA (5'-D(*AP*GP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*GP*AP*GP*A)-3')polymer164952.21Homo sapiens
3C
(C)
DNA (5'-D(*TP*CP*TP*CP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*CP*T)-3')polymer164841.21Homo sapiens
4D
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
5E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6F, G, H
(A, B, C)
waterwater18.028Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight24446.2
Non-Polymers*Number of molecules2
Total formula weight135.2
All*Total formula weight24581.4
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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