7V59
Cryo-EM structure of spyCas9-sgRNA-DNA dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, E | CRISPR-associated endonuclease Cas9/Csn1 | polymer | 1362 | 158111.2 | 2 | UniProt (Q99ZW2) Pfam (PF16593) Pfam (PF16592) Pfam (PF13395) Pfam (PF22702) Pfam (PF16595) In PDB | Streptococcus pyogenes serotype M1 | SpCas9,SpyCas9 |
| 2 | C, G | RNA (115-MER) | polymer | 115 | 37137.1 | 2 | Streptococcus pyogenes | ||
| 3 | D, H | DNA (49-MER) | polymer | 49 | 15040.6 | 2 | Streptococcus pyogenes |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 420577.9 | |
| All* | Total formula weight | 420577.9 |
