7QDT
Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain designed to model dominant negative human mutations.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform Alpha-1 of Thyroid hormone receptor alpha | polymer | 236 | 26725.9 | 1 | UniProt (P10827) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 1 group A member 1,V-erbA-related protein 7,EAR-7,c-erbA-1,c-erbA-alpha |
| 2 | B (A) | 3,5,3'TRIIODOTHYRONINE | non-polymer | 651.0 | 1 | Chemie (T3) | |||
| 3 | C (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26725.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 651.0 | |
| All* | Total formula weight | 27376.9 |
