7Q9U
Crystal structure of the high affinity KRas mutant PDE6D complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | GTPase KRas | polymer | 185 | 21072.0 | 2 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | C, D (DDD, CCC) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 150 | 17441.0 | 2 | UniProt (O43924) Pfam (PF05351) | Homo sapiens (human) | GMP-PDE delta,Protein p17 |
| 3 | E, H (AAA, BBB) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | F, I (AAA, BBB) | FARNESYL | non-polymer | 206.4 | 2 | Chemie (FAR) | |||
| 5 | G, J, M (BBB, DDD, CCC) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | K, L, N, O, P (DDD, CCC) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | Q, R, S, T (AAA, BBB, DDD, CCC) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 1 - 185 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Ser 182 | Lys 182 | conflict |
| Ile 184 | Lys 184 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77026.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1897.7 | |
| All* | Total formula weight | 78923.7 |
