7OS4

Crystal structure of mouse CARM1 in complex with histone H3_13-31 K18

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Histone-arginine methyltransferase CARM1	polymer	371	41985.6	4	UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) In PDB	Mus musculus (Mouse)	Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4
2	E, F, G, H	Histone H3.1	polymer	20	1982.4	4	UniProt (P68433) In PDB	Mus musculus
3	E, F, G, H	(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol	non-polymer		277.3	4	Chemie (QVR)
4		water	water		18.0	60	Chemie (HOH)

Sequence modifications

A, B, C, D: 130 - 497 (UniProt: Q9WVG6)

PDB	External Database	Details
Gly 127	-	expression tag
His 128	-	expression tag
Met 129	-	expression tag

E, F, G, H: 13 - 31 (UniProt: P68433)

PDB	External Database	Details
Ace 12	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	175872.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1109.1
All*	Total formula weight	176981.2

*Water molecules are not included.