7OS4
Crystal structure of mouse CARM1 in complex with histone H3_13-31 K18
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| A | 0018216 | biological_process | peptidyl-arginine methylation |
| B | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| B | 0018216 | biological_process | peptidyl-arginine methylation |
| C | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| C | 0018216 | biological_process | peptidyl-arginine methylation |
| D | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| D | 0018216 | biological_process | peptidyl-arginine methylation |
| E | 0000786 | cellular_component | nucleosome |
| E | 0003677 | molecular_function | DNA binding |
| E | 0030527 | molecular_function | structural constituent of chromatin |
| F | 0000786 | cellular_component | nucleosome |
| F | 0003677 | molecular_function | DNA binding |
| F | 0030527 | molecular_function | structural constituent of chromatin |
| G | 0000786 | cellular_component | nucleosome |
| G | 0003677 | molecular_function | DNA binding |
| G | 0030527 | molecular_function | structural constituent of chromatin |
| H | 0000786 | cellular_component | nucleosome |
| H | 0003677 | molecular_function | DNA binding |
| H | 0030527 | molecular_function | structural constituent of chromatin |
Functional Information from PROSITE/UniProt
| site_id | PS00322 |
| Number of Residues | 7 |
| Details | HISTONE_H3_1 Histone H3 signature 1. KAPRKQL |
| Chain | Residue | Details |
| E | LYS14-LEU20 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| E | LYS14 | |
| B | GLU215 | |
| B | GLU244 | |
| B | SER272 | |
| C | GLN160 | |
| C | ARG169 | |
| C | GLY193 | |
| C | GLU215 | |
| C | GLU244 | |
| C | SER272 | |
| D | GLN160 | |
| F | LYS14 | |
| D | ARG169 | |
| D | GLY193 | |
| D | GLU215 | |
| D | GLU244 | |
| D | SER272 | |
| G | LYS14 | |
| H | LYS14 | |
| A | GLU244 | |
| A | SER272 | |
| B | GLN160 | |
| B | ARG169 | |
| B | GLY193 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:15339660 |
| Chain | Residue | Details |
| E | ARG17 | |
| F | ARG17 | |
| G | ARG17 | |
| H | ARG17 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | LYS18 | |
| E | LYS23 | |
| F | LYS18 | |
| F | LYS23 | |
| G | LYS18 | |
| G | LYS23 | |
| H | LYS18 | |
| H | LYS23 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Citrulline => ECO:0000269|PubMed:15339660 |
| Chain | Residue | Details |
| E | ARG26 | |
| F | ARG26 | |
| G | ARG26 | |
| H | ARG26 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:13678296, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | LYS27 | |
| F | LYS27 | |
| G | LYS27 | |
| H | LYS27 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11441012, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:15735677, ECO:0000269|PubMed:15870105 |
| Chain | Residue | Details |
| E | SER28 | |
| F | SER28 | |
| G | SER28 | |
| H | SER28 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | LIPID: N6-decanoyllysine => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| E | LYS18 | |
| F | LYS18 | |
| G | LYS18 | |
| H | LYS18 |
