7L9A
Crystal structure of BRDT bromodomain 2 in complex with CDD-1102
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bromodomain testis-specific protein | polymer | 135 | 15776.0 | 2 | UniProt (Q58F21) Pfam (PF00439) In PDB | Homo sapiens (Human) | Cancer/testis antigen 9,CT9,RING3-like protein |
2 | A, B | N~1~-(5-{[3-(4-amino-2-methylphenyl)-1-methyl-1H-indazole-5-carbonyl]amino}-2-methylphenyl)-N~4~-methylbenzene-1,4-dicarboxamide | non-polymer | 546.6 | 2 | Chemie (XWP) | |||
3 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
4 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B: 268 - 379 (UniProt: Q58F21)
PDB | External Database | Details |
---|---|---|
Met 245 | - | initiating methionine |
Gly 246 | - | expression tag |
Ser 247 | - | expression tag |
Ser 248 | - | expression tag |
His 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
His 254 | - | expression tag |
Ser 255 | - | expression tag |
Ser 256 | - | expression tag |
Gly 257 | - | expression tag |
Leu 258 | - | expression tag |
Val 259 | - | expression tag |
Pro 260 | - | expression tag |
Arg 261 | - | expression tag |
Gly 262 | - | expression tag |
Ser 263 | - | expression tag |
His 264 | - | expression tag |
Met 265 | - | expression tag |
Ala 266 | - | expression tag |
Ser 267 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31552.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1249.5 | |
All* | Total formula weight | 32801.6 |