7CTH
Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Core protein | polymer | 495 | 54351.7 | 3 | UniProt (Q88636) Pfam (PF00869) Pfam (PF02832) Pfam (PF21659) UniProt (by SIFTS) (P14340) In PDB | Dengue virus 2 | Envelope protein E,Matrix protein,Peptide pr,Protein prM,Small envelope protein M |
2 | F, D, E | Core protein | polymer | 75 | 8345.8 | 3 | UniProt (Q20II5) Pfam (PF01004) UniProt (by SIFTS) (P14340) In PDB | Dengue virus 2 | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
3 | I, H | Single Chain Variable Fragment | polymer | 144 | 15679.2 | 2 | Homo sapiens | ||
4 | M, L | Single Chain Variable Fragment | polymer | 154 | 15632.8 | 2 | Homo sapiens | ||
5 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 250716.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 884.8 | |
All* | Total formula weight | 251601.4 |