7CTH
Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0046983 | molecular_function | protein dimerization activity |
| C | 0046983 | molecular_function | protein dimerization activity |
| D | 0019058 | biological_process | viral life cycle |
| E | 0019058 | biological_process | viral life cycle |
| F | 0019058 | biological_process | viral life cycle |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 102 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| F | THR123-GLY143 | |
| F | ALA150-THR164 | |
| D | THR123-GLY143 | |
| D | ALA150-THR164 | |
| E | THR123-GLY143 | |
| E | ALA150-THR164 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| F | THR144-ARG149 | |
| D | THR144-ARG149 | |
| E | THR144-ARG149 | |
| B | THR473-VAL493 | |
| C | ALA446-ILE466 | |
| C | THR473-VAL493 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host signal peptidase => ECO:0000269|PubMed:2952760 |
| Chain | Residue | Details |
| F | THR164 | |
| D | THR164 | |
| E | THR164 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host signal peptidase => ECO:0000269|PubMed:2952760 |
| Chain | Residue | Details |
| A | ALA495 | |
| B | ALA495 | |
| C | ALA495 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|PROSITE-ProRule:PRU00498 |
| Chain | Residue | Details |
| A | ASN67 | |
| A | ASN153 | |
| B | ASN67 | |
| B | ASN153 | |
| C | ASN67 | |
| C | ASN153 |
