6YAF
AP2 on a membrane containing tyrosine-based cargo peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | AP-2 complex subunit alpha-2 | polymer | 628 | 70310.1 | 1 | UniProt (P18484) Pfam (PF01602) In PDB | Rattus norvegicus (Norway rat) | 100 kDa coated vesicle protein C,Adaptor protein complex AP-2 subunit alpha-2,Adaptor-related protein complex 2 subunit alpha-2,Alpha-adaptin C,Alpha2-adaptin,Clathrin assembly protein complex 2 alpha-C large chain,Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit |
2 | B | AP-2 complex subunit beta | polymer | 944 | 105619.3 | 1 | UniProt (P63010) Pfam (PF01602) Pfam (PF02883) Pfam (PF09066) In PDB | Homo sapiens (Human) | AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit |
3 | M | AP-2 complex subunit mu | polymer | 446 | 51044.1 | 1 | UniProt (P84092) Pfam (PF01217) Pfam (PF00928) In PDB | Rattus norvegicus (Norway rat) | AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein |
4 | P | Tyrosine type cargo signal derived from TGN38 | polymer | 16 | 1940.3 | 1 | UniProt (by SIFTS) (O43493) In PDB | Homo sapiens | |
5 | S | AP-2 complex subunit sigma | polymer | 142 | 17038.7 | 1 | UniProt (P62743) Pfam (PF01217) In PDB | Mus musculus (House mouse) | Adaptor protein complex AP-2 subunit sigma,Adaptor-related protein complex 2 subunit sigma,Clathrin assembly protein 2 sigma small chain,Clathrin coat assembly protein AP17,Clathrin coat-associated protein AP17,Plasma membrane adaptor AP-2 17 kDa protein,Sigma-adaptin 3b,Sigma2-adaptin |
Sequence modifications
A: 1 - 623 (UniProt: P18484)
B: 1 - 937 (UniProt: P63010)
M: 1 - 446 (UniProt: P84092)
PDB | External Database | Details |
---|---|---|
Asp 8 | Glu 8 | conflict |
Glu 272 | - | insertion |
Gly 622 | Pro 621 | conflict |
Gly 624 | - | expression tag |
Leu 625 | - | expression tag |
Val 626 | - | expression tag |
Pro 627 | - | expression tag |
Arg 628 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -6 | - | initiating methionine |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 237 | - | insertion |
Glu 238 | - | insertion |
Gln 239 | - | insertion |
Lys 240 | - | insertion |
Leu 241 | - | insertion |
Ile 242 | - | insertion |
Ser 243 | - | insertion |
Glu 244 | - | insertion |
Glu 245 | - | insertion |
Asp 246 | - | insertion |
Leu 247 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 245952.5 | |
All* | Total formula weight | 245952.5 |